2-(2,2-Dimethyl-2,3-dihydro-1-benzofuran-7-yl­oxy)acetic acid monohydrate

نویسندگان

  • Lin-Tao Yang
  • Jiao Ye
  • Xian-Fu Luo
  • Ai-Xi Hu
چکیده

In the title compound, C(12)H(14)O(4)·H(2)O, the dihydro-benzo-furan ring adopts an envelope conformation with the substituted C atom 0.142 (1) Å out of the least-squares plane. In the crystal, the components are linked via inter-molecular O(water)-H⋯O and O-H⋯O(water) hydrogen-bonding inter-actions, forming a three-dimensional network.

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2-(2,2-Dimethyl-2,3-dihydro-1-benzofuran-7-yl­oxy)-N-(o-tol­yl)acetamide

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Treatment of 5,6-dimethoxy-2-(methylphenylcarbamoyl)-benzofuran-3carboxylic acid with PPA yielded 2,3-dimethoxy-7-methyl-7,12-dihydro-6H-[1]benzofuro-[2,3-c]-[1]-benzazepin-6,12-dione. The analogous 2-[(5,6-dimethoxybenzofuran-2-carbonyl)methylamino]benzoic acid was resistant to cyclization, whereas 2-[(6methoxybenzofuran-2-carbonyl)-amino]benzoic acid underwent cyclization to the corresponding...

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عنوان ژورنال:

دوره 66  شماره 

صفحات  -

تاریخ انتشار 2010